SCHEMBL31476451

SCHEMBL31476451

O=C1C=CC(=O)N1CCCCCCON=Cc1ccc([18F])cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.45
MGLL Q99685 4/20 0.45
HSP90AA1 P07900 1/20 0.45
TLR9 Q9NR96 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
XBP1 P17861 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
RECQL P46063 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
GPR35 Q9HC97 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45
PTGS1 P23219 7/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12949823 1.00 FAAH (0.45) FAAHMGLLHSP90AA1TLR9ALDH1A1
SCHEMBL16922670 0.99 MGLL (0.43) FAAHMGLLHSP90AA1TLR9ALDH1A1
SCHEMBL19952888 0.99 MGLL (0.43) FAAHMGLLHSP90AA1TLR9ALDH1A1
SCHEMBL19381681 0.85 MGLL (0.43) FAAHMGLLHSP90AA1TLR9ALDH1A1
SCHEMBL31653911 0.84 MGLL (0.53) FAAHMGLLLMNAMAPTHTT
SCHEMBL31681317 0.80 GSK3A (0.43) FAAHMGLLHSP90AA1TLR9ALDH1A1
SCHEMBL11939888 0.76 MGLL (0.45) FAAHMGLLHSP90AA1TLR9ALDH1A1
SCHEMBL6077672 0.72 L3MBTL1 (0.43) FAAHLMNAMAPTHTTRECQL
SCHEMBL13381378 0.71 HDAC1 (0.46) FAAHLMNARECQLRAB9ASMN1; SMN2
SCHEMBL14262702 0.69 PLA2G7 (0.45) FAAHLMNAMAPTHTTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214929-A1 SULPHONYL BENZENE DERIVATIVES AND METHODS FOR THE PREPARATION OF SULPHONYL BENZENE DERIVATIVES HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V. (DE) 2025-07-03 US disclosed
WO-2025054616-A1 PLATFORM APPROACH F-18 RADIOLABELING OF VARIOUS PEPTIDES IN AQUEOUS MEDIUM MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2025-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214929-A1 SULPHONYL BENZENE DERIVATIVES AND METHODS FOR THE PREPARATION OF SULPHONYL BENZENE DERIVATIVES TST, BCR, ETV6 FAAH 1685/4885MGLL 4711/4885HSP90AA1 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.