Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219560 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL12522736 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL10216723 | 0.82 | GRIN2D (0.47) | NPC1RAB9AALDH1A1GRIN2DGRIN3B | |
| SCHEMBL410414 | 0.81 | ALDH1A1 (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2GRIN2D | |
| SCHEMBL8870633 | 0.78 | RAB9A (0.46) | NPC1RAB9AALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL8870630 | 0.78 | RAB9A (0.46) | NPC1RAB9AALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL10056240 | 0.77 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2CYP2C19MAPT | |
| SCHEMBL3462265 | 0.77 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2CYP2C19MAPT | |
| SCHEMBL887447 | 0.77 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2CYP2C19MAPT | |
| SCHEMBL381142 | 0.76 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |