Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219560 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAL3MBTL1HPGDHTT | |
| SCHEMBL410414 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL31477679 | 0.83 | NPC1 (0.46) | ALDH1A1LMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10216723 | 0.80 | GRIN2D (0.47) | ALDH1A1LMNARAB9ANPC1MAPT | |
| SCHEMBL887447 | 0.78 | MAPT (0.44) | LMNAL3MBTL1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL3462265 | 0.78 | MAPT (0.44) | LMNAL3MBTL1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL10056240 | 0.78 | MAPT (0.44) | LMNAL3MBTL1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL381142 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL8870697 | 0.77 | ALDH1A1 (0.40) | ALDH1A1LMNAL3MBTL1HPGDHTT | |
| SCHEMBL13168656 | 0.74 | NPC1 (0.48) | ALDH1A1LMNAL3MBTL1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238607-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238607-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | AADAC, NAT1, TNNT2 | ALDH1A1 173/4885LMNA 726/4885L3MBTL1 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.