SCHEMBL3147958

SCHEMBL3147958

O=C(c1ccc(Br)cc1)c1cccc(-c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
KMO O15229 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
ITGA1 P56199 1/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 1/20 0.52
RAB9A P51151 1/20 0.52
AKR1C3 P42330 1/20 0.51
ALDH1A1 P00352 2/20 0.50
TP53 P04637 1/20 0.50
PBRM1 Q86U86 1/20 0.50
CNR2 P34972 1/20 0.49
HSD17B1 P14061 1/20 0.49
HSD17B2 P37059 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11183749 0.89 ATM (0.74) ATMTDP1L3MBTL1KMOHDAC8
SCHEMBL782415 0.87 ATM (0.61) ATMTDP1L3MBTL1KMOHDAC8
SCHEMBL6246063 0.87 MAPK1 (0.65) ATMMEN1KMT2AMAPTLMNA
SCHEMBL177252 0.87 MEN1 (0.67) ATMTDP1L3MBTL1MEN1KMT2A
SCHEMBL16858233 0.87 KMO (0.72) ATMTDP1L3MBTL1KMOHDAC8
SCHEMBL8438374 0.87 ATM (0.77) ATMTDP1L3MBTL1KMOHDAC8
SCHEMBL22172116 0.86 ATM (0.59) ATMTDP1L3MBTL1MEN1KMT2A
Benzophenone SCHEMBL28640629 0.85 ATM (0.57) ATMTDP1L3MBTL1KMOHDAC8
SCHEMBL9126956 0.85 ATM (0.67) ATMTDP1L3MBTL1MEN1KMT2A
Benzophenone SCHEMBL11774383 0.84 ALDH1A1 (0.70) ATMTDP1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476474-B2 Asymmetric styryl derivatives and organic light emitting diode prepared using the same DOOSAN CORPORATION (KR) 2013-07-02 US disclosed
US-8476474-B2 Asymmetric styryl derivatives and organic light emitting diode prepared using the same DOOSAN CORPORATION (KR) 2013-07-02 US disclosed
US-8476474-B2 Asymmetric styryl derivatives and organic light emitting diode prepared using the same DOOSAN CORPORATION (KR) 2013-07-02 US disclosed
US-20100081846-A1 ASYMMETRIC STYRYL DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE PREPARED USING THE SAME DOOSAN CORPORATION (KR) 2010-04-01 US disclosed
US-20100081846-A1 ASYMMETRIC STYRYL DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE PREPARED USING THE SAME DOOSAN CORPORATION (KR) 2010-04-01 US disclosed
US-20100081846-A1 ASYMMETRIC STYRYL DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE PREPARED USING THE SAME DOOSAN CORPORATION (KR) 2010-04-01 US disclosed
WO-2008091130-A1 ASYMMETRIC STYRYL DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE PREPARED USING THE SAME DOOSAN CORPORATION (KR) 2008-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081846-A1 ASYMMETRIC STYRYL DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE PREPARED USING THE SAME ELOVL1, EML4, ACSL1 ATM 1824/4885TDP1 1146/4885L3MBTL1 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.