SCHEMBL177252

SCHEMBL177252

O=C(c1ccccc1)c1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
LMNA P02545 3/20 0.67
MAPT P10636 3/20 0.67
RAB9A P51151 3/20 0.67
ALDH1A1 P00352 2/20 0.61
AKR1C3 P42330 1/20 0.60
MAPK1 P28482 3/20 0.58
SRD5A2 P31213 1/20 0.58
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
ATM Q13315 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CDC25B P30305 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6246063 0.96 MAPK1 (0.65) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL69395 0.93 ALDH1A1 (0.70) MEN1KMT2ALMNAMAPTRAB9A
Benzophenone SCHEMBL11774383 0.93 ALDH1A1 (0.70) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL9355961 0.91 LMNA (0.64) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL10629625 0.91 LMNA (0.64) MEN1KMT2ALMNAMAPTRAB9A
Ethylene SCHEMBL10490013 0.89 ALDH1A1 (0.64) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL13019488 0.89 RAB9A (0.82) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL197633 0.89 RAB9A (0.82) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL3147958 0.87 ATM (0.59) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL41657 0.86 RAB9A (0.78) MEN1KMT2ALMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431157-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2025-02-14 CN disclosed
WO-2023229295-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING PHENYLPROPENE DERIVATIVE AS ACTIVE INGREDIENT 재단법인 대구경북첨단의료산업진흥재단 2023-11-30 WO disclosed
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-24 US disclosed
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-24 US disclosed
WO-2023190508-A1 OPTICAL MEMBER, MATERIAL FOR FORMING OPTICAL MEMBER AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR MANUFACTURING OPTICAL MEMBER 群栄化学工業株式会社 2023-10-05 WO disclosed
WO-2023058524-A1 COMPOUND, RESIN, CURABLE COMPOSITION, CURED PRODUCT, AND OPTICAL MEMBER 群栄化学工業株式会社 2023-04-13 WO disclosed
CN-113698305-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2021-11-26 CN disclosed
US-10862042-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-12-08 US disclosed
US-10770663-B2 Germanium-centered dendrimer compound, and organic optoelectric element comprising same CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2020-09-08 US disclosed
US-20200119276-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-04-16 US disclosed
US-7122699-B2 Process for preparing organic boronic acid derivatives using diboronic acid BORON MOLECULAR LIMITED (AU) 2006-10-17 US disclosed
EP-1019414-B1 PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID COMMW SCIENT IND RES ORG (AU) 2005-06-08 EP disclosed
US-20030220520-A1 Process for preparing organic boronic acid derivatives using diboronic acid COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-11-27 US disclosed
US-6603004-B2 Reacting diboron tetrahydroxide with boronic acid derivatives in presence of group 8-11 metal catalyst; one pot; no need for hydrolysis or hydrogenolysis COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-08-05 US disclosed
US-20020151743-A1 Process for preparing organic boronic avid derivatives using diboronic acid COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2002-10-17 US disclosed
US-6448433-B1 REACTING AN ORGANIC HALIDE WITH TETRAHYDROXYDIBORON; GROUP 8-11 METAL CATALYST COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 2002-09-10 US disclosed
EP-1019414-A4 PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID COMMW SCIENT IND RES ORG (AU) 2002-05-29 EP disclosed
CN-1275984-A Process for preparing organic boronic acid derivatives using diboronic acid COMMW SCIENT IND RES ORG (AU) 2000-12-06 CN disclosed
EP-1019414-A1 PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-07-19 EP disclosed
WO-1999012940-A1 PROCESS FOR PREPARING ORGANIC BORONIC ACID DERIVATIVES USING DIBORONIC ACID COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10770663-B2 Germanium-centered dendrimer compound, and organic optoelectric element comprising same GRK1, OCIAD2, CD40LG MEN1 2072/4885KMT2A 3244/4885LMNA 3847/4885
US-20030220520-A1 Process for preparing organic boronic acid derivatives using diboronic acid BTD, BRAP, DBF4 MEN1 836/4885KMT2A 2202/4885LMNA 2645/4885
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CCNE2, CCNE1 MEN1 220/4885KMT2A 2522/4885LMNA 1464/4885
US-20020151743-A1 Process for preparing organic boronic avid derivatives using diboronic acid BTD, BRAP, BCL6B MEN1 728/4885KMT2A 2744/4885LMNA 2720/4885
US-20200119276-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AFF1, NR2E1 MEN1 974/4885KMT2A 844/4885LMNA 2916/4885
US-10862042-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device NR2E3, AFF1, NR2E1 MEN1 974/4885KMT2A 844/4885LMNA 2916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.