SCHEMBL31480607

SCHEMBL31480607

COC(=O)c1ccc(C2CC3(CCN2)CC3)c(N(C)C)n1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 2/20 0.33
CRBN Q96SW2 2/20 0.31
CYP1A2 P05177 2/20 0.30
TSHR P16473 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
RECQL P46063 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31480509 0.83 CRBN (0.32) CRBNCYP1A2GAAMAPTRECQL
SCHEMBL31480332 0.83 CRBN (0.32) CRBNCYP1A2GAAMAPTRECQL
SCHEMBL31480481 0.75 MAPT (0.30) CRBNMAPT
SCHEMBL31480488 0.73 MAPT (0.31) MAPT
SCHEMBL31480146 0.72 CRBN (0.34) PDE2ACRBN
SCHEMBL31480606 0.72 CRBN (0.33) CRBN
SCHEMBL31480262 0.70 ALDH1A1 (0.38) MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL31480318 0.70 MAPK1 (0.33) CRBN
SCHEMBL31480450 0.70
SCHEMBL16400464 0.70 NPC1 (0.45) TSHRGAAMAPTNPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054361-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2025-03-13 WO disclosed