SCHEMBL31487769

SCHEMBL31487769

CC(C)(C)OC(=O)N1CCC(c2cnn3cc(OCC(F)F)ccc23)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5AP P20292 2/20 0.44
▸ FEN1 P39748 2/20 0.44
▸ GPR119 Q8TDV5 4/20 0.44
▸ HPGD P15428 3/20 0.43
▸ MAPT P10636 2/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ USP2 O75604 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ TP53 P04637 1/20 0.42
▸ RET P07949 2/20 0.42
▸ HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487770 0.89 HPGD (0.42) ALOX5APFEN1GPR119HPGDMAPT
SCHEMBL31488053 0.88 GPR119 (0.44) GPR119HPGDMAPTMEN1USP2
SCHEMBL31488033 0.87 RET (0.49) GPR119HPGDMAPTMEN1USP2
SCHEMBL31487825 0.87 TP53 (0.45) GPR119HPGDMAPTMEN1USP2
SCHEMBL31487885 0.87 GPR119 (0.46) GPR119HPGDMAPTMEN1USP2
SCHEMBL31487807 0.86 GPR119 (0.44) ALOX5APFEN1GPR119HPGDMAPT
SCHEMBL31487960 0.86 RET (0.49) GPR119MAPTTP53RETHTT
SCHEMBL31487790 0.86 ROCK2 (0.41) ALOX5APFEN1GPR119RET
SCHEMBL31487750 0.86 ALDH1A1 (0.53) GPR119HPGDMAPTMEN1KMT2A
SCHEMBL31487817 0.85 TP53 (0.47) GPR119MAPTALDH1A1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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