SCHEMBL31487790

SCHEMBL31487790

CC(C)(C)OC(=O)N1[C@@H]2CC[C@H]1CC(c1cnn3cc(OCC(F)F)ccc13)C2

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ROCK2 O75116 6/20 0.41
▸ PREP P48147 2/20 0.40
▸ CHRM2 P08172 1/20 0.40
▸ CHRM1 P11229 1/20 0.40
▸ CHRM3 P20309 1/20 0.40
▸ EIF2AK4 Q9P2K8 1/20 0.38
▸ RET P07949 3/20 0.38
▸ ALOX5AP P20292 2/20 0.37
▸ FEN1 P39748 2/20 0.37
▸ GPR119 Q8TDV5 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487769 0.86 ALOX5AP (0.44) RETALOX5APFEN1GPR119
SCHEMBL31487770 0.75 HPGD (0.42) ALOX5APFEN1GPR119
SCHEMBL31488053 0.74 GPR119 (0.44) RETGPR119
SCHEMBL31487885 0.73 GPR119 (0.46) RETGPR119
SCHEMBL31487825 0.73 TP53 (0.45) GPR119
SCHEMBL31488033 0.73 RET (0.49) RETGPR119
SCHEMBL31487807 0.72 GPR119 (0.44) RETALOX5APFEN1GPR119
SCHEMBL31487960 0.72 RET (0.49) RETGPR119
SCHEMBL31487857 0.72 ROCK2 (0.39) ROCK2
SCHEMBL31487750 0.71 ALDH1A1 (0.53) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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