Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489405 | 0.88 | PDE10A (0.34) | PDE10APIK3CG | |
| SCHEMBL31489376 | 0.76 | TDP2 (0.32) | PDE10A | |
| SCHEMBL31489399 | 0.76 | KDM4E (0.35) | PDE10AMAPK1KDM4E | |
| SCHEMBL31489910 | 0.75 | CYP11B2 (0.37) | PDE10AMAPK1KDM4EPIK3CG | |
| SCHEMBL31489503 | 0.74 | PDE10A (0.34) | PDE10APIK3CG | |
| SCHEMBL31489179 | 0.73 | KDM4E (0.35) | PDE10AMAPK1KDM4E | |
| SCHEMBL31489203 | 0.72 | PDE10A (0.32) | PDE10AKDM4E | |
| SCHEMBL31489689 | 0.69 | AHR (0.50) | PDE10AMAPK1KDM4E | |
| SCHEMBL31489671 | 0.66 | CA1 (0.32) | KDM4E | |
| SCHEMBL12813257 | 0.65 | AXL (0.47) | PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |