SCHEMBL31489203

SCHEMBL31489203

Cc1ccc(C)n1-c1nc2cc(-c3nc(Br)c(F)cc3F)ccn2n1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.32
AHR P35869 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489376 0.82 TDP2 (0.32) PDE10A
SCHEMBL31489405 0.80 PDE10A (0.34) PDE10A
SCHEMBL31489184 0.76 PIK3CD (0.30)
SCHEMBL31489689 0.76 AHR (0.50) PDE10AAHRKDM4E
SCHEMBL31489351 0.75 ROCK2 (0.35)
SCHEMBL31489379 0.72 KDM4E (0.37) PDE10AAHRKDM4E
SCHEMBL31489371 0.72 PDE10A (0.37) PDE10AKDM4E
SCHEMBL31489179 0.69 KDM4E (0.35) PDE10AKDM4E
SCHEMBL31489137 0.67 KDM4E (0.30) KDM4E
SCHEMBL31489600 0.65 JAK2 (0.44) PDE10AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed