SCHEMBL31489376

SCHEMBL31489376

Cc1ccc(C)n1-c1nc2cc(-c3nc(Cl)ccc3F)ccn2n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.32
PDE10A Q9Y233 3/20 0.32
HTR6 P50406 1/20 0.31
KCNN3 Q9UGI6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489405 0.84 PDE10A (0.34) PDE10A
SCHEMBL31489203 0.82 PDE10A (0.32) PDE10A
SCHEMBL31489351 0.81 ROCK2 (0.35)
SCHEMBL31489184 0.79 PIK3CD (0.30)
SCHEMBL31489179 0.78 KDM4E (0.35) TDP2PDE10A
SCHEMBL31489503 0.77 PDE10A (0.34) TDP2PDE10A
SCHEMBL31489371 0.76 PDE10A (0.37) PDE10A
SCHEMBL31489910 0.75 CYP11B2 (0.37) TDP2PDE10A
SCHEMBL31489399 0.73 KDM4E (0.35) PDE10A
SCHEMBL31489689 0.69 AHR (0.50) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed