Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31495025 | 0.83 | MEN1 (0.46) | TNFMEN1KMT2AMAPTNPC1 | |
| SCHEMBL31495149 | 0.79 | MAPT (0.50) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL30615490 | 0.72 | L3MBTL1 (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL21467314 | 0.72 | L3MBTL1 (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL31495118 | 0.70 | MEN1 (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL145899 | 0.70 | KMT2A (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL30391374 | 0.69 | ALDH1A1 (0.42) | MEN1KMT2AMAPTMAPK1NPSR1 | |
| SCHEMBL15227141 | 0.68 | KMT2A (0.41) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL4143510 | 0.68 | KMT2A (0.41) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL30855342 | 0.68 | KMT2A (0.41) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |