SCHEMBL31496201

SCHEMBL31496201

CC(C)(C)OC(=O)N1CCC2(CC1)CC(Oc1ccc(-c3cc4c(cc3C(F)F)NCCC4)cn1)C2

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 2/20 0.40
▸ NAMPT P43490 5/20 0.38
▸ GPR119 Q8TDV5 5/20 0.37
▸ CREBBP Q92793 2/20 0.36
▸ BRD4 O60885 1/20 0.36
▸ TBK1 Q9UHD2 2/20 0.34
▸ HDAC1 Q13547 1/20 0.34
▸ HDAC2 Q92769 1/20 0.34
▸ USP1 O94782 1/20 0.34
▸ PIK3CD O00329 1/20 0.34
▸ KDM1A O60341 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31692747 0.81 GPR119 (0.42) GPR119
SCHEMBL31692690 0.76 MAPK1 (0.39) NAMPTGPR119HDAC1HDAC2
SCHEMBL31496087 0.74 CREBBP (0.63) CREBBPBRD4
SCHEMBL30329049 0.74 GPR119 (0.48) MGLLGPR119
SCHEMBL31496189 0.73 TBK1 (0.43) GPR119CREBBPBRD4TBK1
SCHEMBL25198716 0.73 CREBBP (0.41) CREBBPBRD4
SCHEMBL30395478 0.73 CREBBP (0.41) CREBBPBRD4
SCHEMBL20396131 0.72 MGLL (0.46) MGLLNAMPTGPR119TBK1KDM1A
SCHEMBL31496147 0.72 DGAT1 (0.56) MGLLNAMPTGPR119
SCHEMBL25193494 0.71 PDK4 (0.47) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. 2025-05-01 — — US disclosed
WO-2025081092-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. (US) 2025-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS AR, SHBG, FSHR MGLL 3789/4885NAMPT 3920/4885GPR119 245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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