Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1B | P36896 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3774439 | 0.99 | ACVR1B (0.39) | ACVR1BTGFBR1ACVR1FYNMAP3K11 | |
| SCHEMBL3146461 | 0.84 | FPR2 (0.39) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3767824 | 0.83 | FPR2 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL3151157 | 0.82 | CHRNB1 (0.49) | FYNCYP1A1CYP1B1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3147131 | 0.81 | CHRNB1 (0.48) | FYNCYP1A1CYP1B1CYP11B1CYP11B2 | |
| SCHEMBL3137034 | 0.81 | INPPL1 (0.41) | CYP1A1CYP1B1 | |
| SCHEMBL3150645 | 0.81 | CYP11B1 (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL3147229 | 0.80 | CHRNB2 (0.49) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3141660 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3765553 | 0.79 | CHRNB2 (0.48) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |