Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245094 | 0.89 | CYP17A1 (0.61) | SMN1; SMN2CYP17A1HDAC8MEN1KMT2A | |
| SCHEMBL2987817 | 0.88 | RAB9A (0.74) | ADAMTS4NPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL22416647 | 0.84 | ADAMTS4 (0.46) | ADAMTS4NPC1RAB9ASMN1; SMN2CYP17A1 | |
| SCHEMBL31509474 | 0.81 | LTA4H (0.51) | ADAMTS4NPC1RAB9ASMN1; SMN2CYP17A1 | |
| SCHEMBL594716 | 0.80 | CYP17A1 (0.52) | ADAMTS4CYP17A1ALDH1A1 | |
| SCHEMBL8575829 | 0.80 | KMT2A (0.63) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31703448 | 0.79 | MAOB (0.58) | NPC1RAB9ASMN1; SMN2LTA4HSIRT2 | |
| SCHEMBL31703470 | 0.79 | MAOB (0.58) | NPC1RAB9ASMN1; SMN2SIRT2PPARA | |
| SCHEMBL627043 | 0.79 | ALDH1A1 (0.53) | ADAMTS4NPC1RAB9ASMN1; SMN2CYP17A1 | |
| SCHEMBL7955791 | 0.79 | CYP17A1 (0.57) | ADAMTS4SMN1; SMN2CYP17A1HDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085489-A1 | GSPT1-DEGRADING COMPOUNDS, ANTI-CD33 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-24 | — | — | WO | disclosed |