Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31509543 | 0.82 | RAB9A (0.49) | LTA4HADAMTS4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31509580 | 0.81 | ADAMTS4 (0.57) | LTA4HADAMTS4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31509586 | 0.80 | HDAC1 (0.48) | LTA4HADAMTS4RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL2987817 | 0.80 | RAB9A (0.74) | LTA4HADAMTS4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21781875 | 0.80 | CYP17A1 (0.52) | HDAC1CYP17A1MAPKAPK2 | |
| SCHEMBL31509544 | 0.78 | LTA4H (0.42) | LTA4HADAMTS4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7698017 | 0.76 | CYP17A1 (0.52) | LTA4HHDAC1HDAC8CYP17A1MAPKAPK2 | |
| SCHEMBL31509539 | 0.74 | MAOB (0.51) | ALDH1A1 | |
| SCHEMBL7043590 | 0.74 | LTA4H (0.62) | LTA4HRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL34480 | 0.73 | CYP17A1 (0.59) | HDAC8CYP17A1PPARGPPARAMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085489-A1 | GSPT1-DEGRADING COMPOUNDS, ANTI-CD33 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-24 | — | — | WO | disclosed |