Sugi Predict

Sugi Predict / Compounds / SCHEMBL315117

SCHEMBL315117

SCHEMBL315117

COC(=O)C(Cc1ccc(O)cc1)NC(C)=O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ NPSR1 Q6W5P4 2/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ LNPEP Q9UIQ6 3/20 0.60
▸ TSHR P16473 1/20 0.60
▸ MDM4 O15151 1/20 0.60
▸ MDM2 Q00987 1/20 0.60
▸ ESR1 P03372 1/20 0.58
▸ ESR2 Q92731 1/20 0.58
▸ NLRP3 Q96P20 1/20 0.55
▸ TACR1 P25103 1/20 0.53
▸ ALDH1A1 P00352 1/20 0.53
▸ ERAP2 Q6P179 2/20 0.53
▸ ERAP1 Q9NZ08 1/20 0.53
▸ KDR P35968 1/20 0.52
▸ ATM Q13315 1/20 0.51
▸ GRIA1 P42261 1/20 0.51
▸ MIF P14174 1/20 0.50
▸ LCK P06239 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3050135 1.00 NPSR1 (0.61) NPSR1KMT2ALNPEPTSHRMDM4
SCHEMBL2522737 1.00 NPSR1 (0.61) NPSR1KMT2ALNPEPTSHRMDM4
SCHEMBL1856782 0.94 TSHR (0.62) NPSR1KMT2ALNPEPTSHRMDM4
Acetyl Tyrosine Ethyl Ester SCHEMBL14370511 0.88 TACR1 (0.58) NPSR1KMT2ALNPEPTSHRMDM4
Acetyl Tyrosine Ethyl Ester SCHEMBL468858 0.88 TACR1 (0.58) NPSR1KMT2ALNPEPTSHRMDM4
Acetyl Tyrosine Ethyl Ester SCHEMBL468756 0.88 TACR1 (0.58) NPSR1KMT2ALNPEPTSHRMDM4
SCHEMBL27310245 0.88 TACR1 (0.51) NPSR1KMT2ALNPEPTSHRMDM4
SCHEMBL17176127 0.87 ATM (0.63) NPSR1KMT2ALNPEPTSHRTACR1
SCHEMBL14542254 0.87 ALDH1A1 (0.54) NPSR1KMT2ALNPEPTSHRMDM4
SCHEMBL7604061 0.87 TSHR (0.64) NPSR1KMT2ALNPEPTSHRMDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105885467-B A kind of environmental protection type dye using Acetyl Tyrosine as coupling component and preparation method thereof 武汉远大弘元股份有限公司 2017-10-03 — — CN claimed
CN-105885467-A Environment-friendly dye with acetyltyrosine used as coupling component and method for preparing environment-friendly dye 武汉远大弘元股份有限公司 2016-08-24 — — CN claimed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 — — US claimed
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 — — WO claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 — — US claimed
EP-3856734-B1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2025-09-24 — — EP disclosed
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-07-20 — — US disclosed
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-07-20 — — US disclosed
CN-111592490-B Preparation method of key intermediate of roxasistat 浙江工业大学 2022-04-22 — — CN disclosed
US-20220002263-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2022-01-06 — — US disclosed
EP-3856734-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION Studiengesellschaft Kohle mbH (DE) 2021-08-04 — — EP disclosed
CN-111592490-A Preparation method of key intermediate of roxasistat 浙江工业大学 2020-08-28 — — CN disclosed
US-20070191604-A1 Novel compounds that are ERK inhibitors SCHERING CORPORATION 2007-08-16 — — US disclosed
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-14 — — US disclosed
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-14 — — US disclosed
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-14 — — US disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 — — WO disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 — — WO disclosed
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 — — WO disclosed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION CFH, DOHH, CTSH NPSR1 3393/4885KMT2A 867/4885LNPEP 1812/4885
US-20220002263-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION CFH, DOHH, CTSH NPSR1 3393/4885KMT2A 867/4885LNPEP 1812/4885
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM DDT, DHCR7, NOTUM NPSR1 271/4885KMT2A 3920/4885LNPEP 1851/4885
US-20070191604-A1 Novel compounds that are ERK inhibitors MAPK1, MAPK4, MAPKAPK2 NPSR1 3054/4885KMT2A 1822/4885LNPEP 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.