SCHEMBL315157

SCHEMBL315157

COC(=O)COC(=O)C(Cc1ccc(OCC(=O)OC)cc1)NC(=O)CO

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
GLA P06280 1/20 0.46
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
HDAC8 Q9BY41 6/20 0.45
HDAC1 Q13547 5/20 0.45
HDAC6 Q9UBN7 5/20 0.45
HDAC3 O15379 3/20 0.45
HDAC4 P56524 3/20 0.45
HDAC7 Q8WUI4 3/20 0.45
HDAC2 Q92769 3/20 0.45
HDAC10 Q969S8 3/20 0.45
HDAC11 Q96DB2 3/20 0.45
HDAC9 Q9UKV0 3/20 0.45
HDAC5 Q9UQL6 3/20 0.45
GPR34 Q9UPC5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313537 0.94 MEN1 (0.58) MEN1KMT2AALDH1A1LMNAGLA
SCHEMBL12534524 0.90 ALDH1A1 (0.47) MEN1KMT2AALDH1A1LMNAGLA
SCHEMBL2619552 0.89 ALDH1A1 (0.42) MEN1KMT2AALDH1A1LMNAHDAC8
SCHEMBL15214440 0.88 GLA (0.46) MEN1KMT2AALDH1A1LMNAGLA
SCHEMBL314059 0.87 MDM4 (0.52) KMT2AALDH1A1HDAC1HDAC6
SCHEMBL313085 0.87 ITGB3 (0.50) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL313677 0.85 ITGB3 (0.48) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL1862350 0.84 MEN1 (0.61) MEN1KMT2AALDH1A1LMNAHDAC1
SCHEMBL2619550 0.83 MEN1 (0.58) MEN1KMT2AALDH1A1LMNAHDAC8
SCHEMBL1858694 0.81 ALDH1A1 (0.56) MEN1KMT2AALDH1A1LMNAHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-20130317118-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-11-28 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 MEN1 2243/4885KMT2A 3572/4885ALDH1A1 1912/4885
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 MEN1 2243/4885KMT2A 3572/4885ALDH1A1 1912/4885
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 MEN1 2243/4885KMT2A 3572/4885ALDH1A1 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.