Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793892 | 1.00 | MAOB (0.46) | MAOBPNMTCD44MAOAOXTR | |
| Sulfuric Acid SCHEMBL31518346 | 0.91 | PNMT (0.50) | MAOBPNMTCD44MAOAOXTR | |
| SCHEMBL29351494 | 0.80 | — | — | |
| SCHEMBL13590042 | 0.80 | PNMT (0.65) | MAOBPNMTCD44OXTR | |
| SCHEMBL10612 | 0.80 | — | — | |
| SCHEMBL11365140 | 0.78 | CES1 (0.48) | MAOBMAOAKEAP1NPC1 | |
| SCHEMBL620774 | 0.78 | IKBKB (0.44) | CD44 | |
| Hydrochloric Acid SCHEMBL4702076 | 0.77 | PNMT (0.62) | MAOBPNMTCD44OXTR | |
| Ammonia Solution, Strong SCHEMBL16296133 | 0.77 | PNMT (0.62) | MAOBPNMTCD44OXTR | |
| Methane SCHEMBL11147358 | 0.77 | PNMT (0.62) | MAOBPNMTCD44OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119959406-A | Method for detecting cis-all-hydrogen isoindole and trans-isomer in salt thereof | 北京四环科宝制药股份有限公司 | 2025-05-09 | — | — | CN | disclosed |