Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435618 | 0.88 | LMNA (0.44) | LMNACYP2A6CYP1A2SIGMAR1AHR | |
| SCHEMBL218474 | 0.88 | LMNA (0.44) | LMNACYP2A6CYP1A2SIGMAR1AHR | |
| SCHEMBL434059 | 0.86 | HTT (0.44) | LMNACYP2A6CYP1A2SIGMAR1HTR2C | |
| SCHEMBL8125538 | 0.86 | HTT (0.44) | LMNACYP2A6CYP1A2SIGMAR1HTR2C | |
| SCHEMBL6077152 | 0.78 | PDE7A (0.37) | LMNACYP2A6CYP1A2SIGMAR1PTGS2 | |
| SCHEMBL6503383 | 0.78 | MAOA (0.43) | LMNACYP1A2SIGMAR1RAB9AMAOB | |
| SCHEMBL6075715 | 0.78 | NPC1 (0.39) | LMNACYP2A6CYP1A2SIGMAR1ALOX5 | |
| SCHEMBL3952742 | 0.75 | CYP1A2 (0.73) | LMNACYP2A6CYP1A2AHRALOX5 | |
| SCHEMBL11165087 | 0.75 | CYP1A2 (0.73) | LMNACYP2A6CYP1A2AHRALOX5 | |
| SCHEMBL28215 | 0.75 | CYP1A2 (0.73) | LMNACYP2A6CYP1A2AHRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | claimed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | claimed |
| WO-2017189868-A1 | SERINE REPLACEMENT POLYMYXIN ANALOGUES USEFUL AS ANTIBIOTIC POTENTIATORS | SPERO OPCO (US) | 2017-11-02 | — | — | WO | claimed |
| EP-2794573-B1 | NOVEL INSECTICIDAL AROMATIC AMIDES | BAYER IP GMBH (DE) | 2017-08-30 | — | — | EP | claimed |
| US-9670208-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-06-06 | — | — | US | claimed |
| US-9573966-B2 | Anti-cancer activity of novel bicyclic heterocycles | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2017-02-21 | — | — | US | claimed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | claimed |
| EP-2616077-B1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | UNIV LEUVEN KATH (BE) | 2016-08-31 | — | — | EP | claimed |
| US-9204645-B2 | Insecticidal aromatic amides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | claimed |
| CN-1026649-C | Improved insecticide composition, method for the production thereof and use thereof | BRITISH TECHNOLOGY GROUP CO LT (GB) | 1994-11-23 | — | — | CN | claimed |
| CN-1021434-C | PROCESS FOR PREPARING IMPROVED PESTICIDAL CHEMICAL COMPOUNDS | NAT RES DEV (GB) | 1993-06-30 | — | — | CN | claimed |
| US-5051447-A | Applying aromatic oximes to plants, seeds or soils | BASF AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | claimed |
| EP-0179788-B1 | PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-06-12 | — | — | EP | claimed |
| CN-1049843-A | The preparation method of improved agricultural chemical compound | NAT RES DEV (GB) | 1991-03-13 | — | — | CN | claimed |
| EP-0354571-A1 | Oximethers, method for their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-02-14 | — | — | EP | claimed |
| US-4777185-A | Phenyl phenoxyphenyl propenyl cyclopropane pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-10-11 | — | — | US | claimed |
| CN-85102916-A | Improvements relating to pesticides | — | 1986-10-15 | — | — | CN | claimed |
| EP-0179788-A1 | PESTICIDES. | NAT RES DEV (GB) | 1986-05-07 | — | — | EP | claimed |
| WO-1985004651-A1 | IMPROVEMENTS RELATING TO PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | TTBK1, MAP3K1, TNNI3K | LMNA 1573/4885CYP2A6 4669/4885CYP1A2 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.