Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NQO2 | P16083 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | MAX | P61244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206718 | 0.76 | ACHE (0.61) | MAPTALDH1A1KMT2AGAANPSR1 | |
| SCHEMBL9480318 | 0.73 | MAPT (0.48) | MAPTALDH1A1KMT2AGAAACHE | |
| SCHEMBL410281 | 0.71 | MAPT (0.46) | MAPTALDH1A1KMT2AGAAKDM4E | |
| SCHEMBL558407 | 0.71 | TDP1 (0.50) | MAPTALDH1A1KMT2AGAARAB9A | |
| SCHEMBL9479792 | 0.71 | MAPT (0.46) | MAPTALDH1A1KMT2AGAAACHE | |
| SCHEMBL9481868 | 0.71 | MAPT (0.46) | MAPTALDH1A1KMT2AGAANPSR1 | |
| SCHEMBL6295848 | 0.70 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2AGAARAB9A | |
| SCHEMBL11620950 | 0.69 | MAPT (0.41) | MAPTALDH1A1KMT2AGAARAB9A | |
| SCHEMBL269884 | 0.68 | ALDH1A1 (0.46) | MAPTALDH1A1KMT2AGAANPSR1 | |
| SCHEMBL578186 | 0.68 | MAPT (0.42) | MAPTALDH1A1KMT2AGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558587-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES AS IMMUNOMODULATORY AGENTS | Pfizer Products Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| US-20040097554-A1 | Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents | PFIZER INC | 2004-05-20 | — | — | US | claimed |
| WO-2004039375-A1 | METHODS OF USING CCR1 ANTAGONISTS AS IMMUNOMODULATORY AGENTS | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | claimed |
| WO-2004039787-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES AS IMMUNOMODULATORY AGENTS | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | claimed |
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | PFIZER INC | 2004-05-06 | — | — | US | claimed |
| US-20020198207-A1 | Novel Hexanoic acid derivatives | KATH JOHN CHARLES (US) | 2002-12-26 | — | — | US | claimed |
| US-6403587-B1 | AUTOIMMUNE DISEASES, ACUTE AND CHRONIC INFLAMMATORY CONDITIONS, ALLERGIC CONDITIONS, INFECTION ASSOCIATED WITH INFLAMMATION, VIRAL, TRANSPLANTATION TISSUE REJECTION, ATHEROSCLEROSIS, RESTENOSIS, HIV INFECTIVITY, AND | PFIZER INC. | 2002-06-11 | — | — | US | claimed |
| US-6302924-B1 | THERMAL PRINTING | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-16 | — | — | US | claimed |
| CN-1057772-C | Compounds and compositions for treating immunomodulatory inflammation | AXYS PHARMACEUTICAL CORP (US) | 2000-10-25 | — | — | CN | claimed |
| EP-0966443-A1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR | PFIZER INC. (US) | 1999-12-29 | — | — | EP | claimed |
| EP-0713488-B1 | [1,3,4]TRIAZOLO [1,5-AL]PYRIDINES USED AS INTERMEDIATE PRODUCTS FOR THE SYNTHESIS OF DYES | BASF AG (DE) | 1997-10-15 | — | — | EP | claimed |
| EP-0509302-B1 | Process for transfer of methine dyes | BASF AG (DE) | 1997-01-29 | — | — | EP | claimed |
| US-5525623-A | TRYPTASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-06-11 | — | — | US | claimed |
| CN-1119019-A | Compositions and methods for treating immunomodulatory inflammation | ARRIS PHARM CORP (US) | 1996-03-20 | — | — | CN | claimed |
| EP-0688337-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNOMEDIATED INFLAMMATORY DISORDERS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1995-12-27 | — | — | EP | claimed |
| EP-0413226-B1 | [1,2,4]Triazo [1,5-a]pyridine | BASF AG (DE) | 1995-05-24 | — | — | EP | claimed |
| WO-1994020527-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNOMEDIATED INFLAMMATORY DISORDERS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1994-09-15 | — | — | WO | claimed |
| US-5256624-A | Transfer of methine dyes | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | claimed |
| EP-0509302-A1 | Process for transfer of methine dyes | BASF Aktiengesellschaft (DE) | 1992-10-21 | — | — | EP | claimed |
| US-5101028-A | Intermediates for dyes | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087571-A1 | Methods of using CCR1 antagonists as immunomodulatory agents | CCR1, CCR3, CCRL2 | MAPT 4783/4885ALDH1A1 438/4885KMT2A 2266/4885 |
| US-20020198207-A1 | Novel Hexanoic acid derivatives | HCAR3, HCAR1, FFAR1 | MAPT 4547/4885ALDH1A1 169/4885KMT2A 2539/4885 |
| US-20040097554-A1 | Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents | CCR1, HCAR1, CCR3 | MAPT 4041/4885ALDH1A1 303/4885KMT2A 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.