Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522153 | 0.92 | ADRA2C (0.65) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL31522179 | 0.89 | ADRA2C (0.72) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL31522181 | 0.86 | ADRA2C (0.72) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL18666145 | 0.84 | ADRA2C (1.00) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL25386995 | 0.81 | MTNR1B (0.75) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL18666586 | 0.80 | ADRA2C (0.81) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL18666165 | 0.79 | ADRA2C (0.78) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL31522182 | 0.78 | POLB (0.44) | ADRA2CL3MBTL1POLBGAAATM | |
| SCHEMBL11643242 | 0.78 | MAPK1 (0.55) | L3MBTL1POLBMTNR1BALDH1A1SMN1; SMN2 | |
| SCHEMBL1645833 | 0.77 | ADRA2C (0.67) | ADRA2CPOLBALDH1A1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |