Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522180 | 0.94 | MTNR1B (0.50) | POLBADRA2CL3MBTL1ATMGAA | |
| SCHEMBL26270707 | 0.84 | MTNR1B (0.64) | POLBADRA2CL3MBTL1ATMGAA | |
| SCHEMBL31522174 | 0.78 | ADRA2C (0.72) | POLBADRA2CL3MBTL1ATMGAA | |
| SCHEMBL8033873 | 0.77 | BRD4 (0.59) | POLBL3MBTL1GAALMNASMN1; SMN2 | |
| SCHEMBL10845357 | 0.76 | MAPT (0.47) | POLBGAALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29193980 | 0.76 | LMNA (0.45) | POLBLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17414151 | 0.76 | LPAR1 (0.50) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL31522156 | 0.75 | LMNA (0.43) | POLBL3MBTL1MTNR1BLMNASMN1; SMN2 | |
| SCHEMBL12330707 | 0.75 | ALDH1A1 (0.55) | POLBL3MBTL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15145823 | 0.75 | L3MBTL1 (0.51) | POLBL3MBTL1LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |