Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522181 | 0.95 | ADRA2C (0.72) | ADRA2CMTNR1BALDH1A1TSHRUSP2 | |
| SCHEMBL31522174 | 0.92 | ADRA2C (0.72) | ADRA2CMTNR1BALDH1A1TSHRUSP2 | |
| SCHEMBL25386995 | 0.87 | MTNR1B (0.75) | ADRA2CMTNR1BALDH1A1TSHRUSP2 | |
| SCHEMBL31522179 | 0.85 | ADRA2C (0.72) | ADRA2CMTNR1BALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL31522166 | 0.81 | LMNA (0.50) | MTNR1BALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL31522180 | 0.80 | MTNR1B (0.50) | ADRA2CMTNR1BALDH1A1TSHRUSP2 | |
| SCHEMBL18666145 | 0.80 | ADRA2C (1.00) | ADRA2CALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL1645833 | 0.79 | ADRA2C (0.67) | ADRA2CALDH1A1TSHRUSP2KMT2A | |
| Hydrochloric Acid SCHEMBL7422552 | 0.78 | ADRA2C (0.65) | ADRA2CALDH1A1TSHRUSP2KMT2A | |
| SCHEMBL18666586 | 0.76 | ADRA2C (0.81) | ADRA2CMTNR1BALDH1A1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |