Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.72 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522174 | 0.89 | ADRA2C (0.72) | ADRA2CMTNR1BALDH1A1L3MBTL1POLB | |
| SCHEMBL25386995 | 0.87 | MTNR1B (0.75) | ADRA2CMTNR1BALDH1A1L3MBTL1POLB | |
| SCHEMBL31522153 | 0.85 | ADRA2C (0.65) | ADRA2CMTNR1BALDH1A1L3MBTL1POLB | |
| SCHEMBL18666145 | 0.84 | ADRA2C (1.00) | ADRA2CALDH1A1L3MBTL1POLBGAA | |
| SCHEMBL11645789 | 0.82 | MAPK1 (0.60) | MTNR1BALDH1A1POLBMEN1LMNA | |
| SCHEMBL31522181 | 0.81 | ADRA2C (0.72) | ADRA2CMTNR1BALDH1A1L3MBTL1POLB | |
| SCHEMBL11158642 | 0.80 | ALDH1A1 (0.55) | ADRA2CMTNR1BALDH1A1L3MBTL1GAA | |
| SCHEMBL11641172 | 0.78 | LTA4H (0.67) | MTNR1BALDH1A1L3MBTL1POLBGAA | |
| SCHEMBL18666586 | 0.78 | ADRA2C (0.81) | ADRA2CMTNR1BALDH1A1L3MBTL1POLB | |
| SCHEMBL11643915 | 0.77 | ADRA2C (0.55) | ADRA2CMTNR1BALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |