Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | DGAT2 | Q96PD7 | 5/20 | 0.47 |
| ▸ | PYGM | P11217 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666151 | 0.90 | MTNR1B (0.63) | MTNR1BPYGMALDH1A1POLBKDM4E | |
| SCHEMBL30567101 | 0.90 | MTNR1B (0.63) | MTNR1BPYGMALDH1A1POLBKDM4E | |
| SCHEMBL18666157 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBKDRKDM4ESMN1; SMN2 | |
| SCHEMBL18666149 | 0.82 | ALDH1A1 (0.55) | MTNR1BALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL31120712 | 0.82 | MTNR1B (0.53) | MTNR1BALDH1A1POLBAURKAMET | |
| SCHEMBL18666146 | 0.80 | ADRA2C (0.54) | MTNR1BALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL29660113 | 0.80 | ADRA2C (0.54) | MTNR1BALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL18666150 | 0.79 | MTNR1B (0.47) | MTNR1BALDH1A1KDM4ERECQL | |
| SCHEMBL24724259 | 0.79 | MTNR1B (0.69) | MTNR1BPYGMALDH1A1POLBKDM4E | |
| SCHEMBL25388461 | 0.78 | MTNR1B (0.62) | MTNR1BPYGMALDH1A1POLBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |