SCHEMBL31523025

SCHEMBL31523025

Nc1c(Br)cnc(C(F)(F)F)c1F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MBOAT4 Q96T53 1/20 0.34
▸ HTT P42858 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31523105 0.85 MBOAT4 (0.30) MBOAT4
SCHEMBL21598489 0.82 MBOAT4 (0.35) MBOAT4HTTKMT2A
SCHEMBL30060695 0.76 TRPV4 (0.32) —
SCHEMBL23832855 0.76 ENPP3 (0.37) —
SCHEMBL23976836 0.76 TRPV4 (0.32) —
SCHEMBL23976834 0.76 MBOAT4 (0.32) MBOAT4
SCHEMBL16857376 0.74 MBOAT4 (0.32) MBOAT4
SCHEMBL31522940 0.72 KDM4E (0.31) —
SCHEMBL31523485 0.72 ULK1 (0.32) —
SCHEMBL31523480 0.71 KDM4E (0.41) HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346600-A1 TRICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2025-11-13 — — US disclosed
WO-2025054488-A1 TRICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. (US) 2025-03-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346600-A1 TRICYCLIC DERIVATIVES AND RELATED USES WRN, RECQL, BLM MBOAT4 4712/4885HTT 1548/4885KMT2A 2611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback