Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833456 | 0.81 | POLB (0.46) | RAB9AL3MBTL1POLBHSD17B10CA12 | |
| SCHEMBL31535836 | 0.81 | TP53 (0.40) | RAB9AL3MBTL1POLBHSD17B10CA12 | |
| SCHEMBL20304607 | 0.81 | MAPT (0.43) | RAB9AL3MBTL1POLBHSD17B10CA12 | |
| SCHEMBL26693895 | 0.81 | GPBAR1 (0.42) | RAB9AL3MBTL1POLBHSD17B10CA12 | |
| SCHEMBL20680345 | 0.81 | ALDH1A1 (0.41) | RAB9AL3MBTL1POLBHSD17B10CA12 | |
| SCHEMBL29837605 | 0.77 | CYP1A2 (0.45) | RAB9AL3MBTL1POLBALDH1A1MAPT | |
| SCHEMBL26694167 | 0.77 | CYP1A2 (0.45) | RAB9AL3MBTL1POLBALDH1A1MAPT | |
| SCHEMBL22532251 | 0.77 | MAOA (0.46) | RAB9AL3MBTL1POLBALDH1A1MAPT | |
| SCHEMBL23833481 | 0.76 | ALDH1A1 (0.51) | L3MBTL1POLBALDH1A1MAPTGAA | |
| SCHEMBL31296540 | 0.75 | L3MBTL1 (0.49) | RAB9AL3MBTL1ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | RAB9A 2227/4885L3MBTL1 1245/4885POLB 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.