Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.65 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177704 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30209491 | 0.91 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1368972 | 0.91 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7907957 | 0.91 | ALDH1A1 (0.74) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL554296 | 0.90 | GAA (0.70) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29467789 | 0.90 | GAA (0.70) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL395026 | 0.86 | CYP1A2 (0.64) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL29366638 | 0.86 | CYP1A2 (0.64) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL4402154 | 0.84 | LTA4H (0.60) | MAPTMEN1KMT2AGAAMAOA | |
| SCHEMBL29860094 | 0.84 | LTA4H (0.60) | MAPTMEN1KMT2AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912506-A | 1, 2-Diaza-5-carboxamide compound, preparation method and application thereof | 沈阳药科大学 | 2025-05-02 | — | — | CN | disclosed |
| CN-113164495-B | Covalent targeting of E3 ligases | 加利福尼亚大学董事会 | 2025-04-22 | — | — | CN | disclosed |
| US-20250120982-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250120982-A1 | COVALENT TARGETING OF E3 LIGASES | STUB1, XIAP, RBX1 | ALDH1A1 2485/4885MAPT 2132/4885MEN1 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.