SCHEMBL1368972

SCHEMBL1368972

Nc1ccc(Oc2ccc3ccc(Oc4ccc(N)cc4)cc3c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.67
TDP1 Q9NUW8 2/20 0.67
CYP3A4 P08684 2/20 0.67
TSHR P16473 1/20 0.67
MAPT P10636 5/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
GAA P10253 2/20 0.64
MITF O75030 1/20 0.64
GFER P55789 1/20 0.64
NLRP1 Q9C000 1/20 0.64
NOD2 Q9HC29 1/20 0.64
MAOA P21397 2/20 0.56
MAOB P27338 2/20 0.54
TEAD4 Q15561 1/20 0.54
POLB P06746 1/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPK1 P28482 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30209491 1.00 ALDH1A1 (0.67) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL7907957 0.95 ALDH1A1 (0.74) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL31536331 0.91 ALDH1A1 (0.65) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL1177704 0.91 ALDH1A1 (0.65) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL1283859 0.85 SMN1; SMN2 (0.75) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL10576066 0.82 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL65211 0.82 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL4455485 0.82 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL2013073 0.82 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL4446167 0.82 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2580261-A1 MAIN-CHAIN BENZOXAZINE OLIGOMER COMPOSITIONS, AND METHOD FOR THE PREPARATION THEREOF Momentive Specialty Chemicals Research S.A. (BE) 2013-04-17 EP claimed
US-20110288260-A1 MAIN-CHAIN BENZOXAZINE OLIGOMER COMPOSITIONS, AND METHOD FOR THE PREPARATION THEREOF HEXION INC. (FORMERLY KNOWN AS MOMENTIVE SPECIALTY CHEMICALS INC.) 2011-11-24 US claimed
WO-2011116232-A1 MAIN-CHAIN BENZOXAZINE OLIGOMER COMPOSITIONS, AND METHOD FOR THE PREPARATION THEREOF MOMENTIVE SPECIALTY CHEMICALS INC. (US) 2011-09-22 WO claimed
US-5702503-A MULTILAYER UOP (US) 1997-12-30 US claimed
EP-0703819-A4 COMPOSITE GAS SEPARATION MEMBRANES AND MAKING THEREOF UOP INC (US) 1996-10-02 EP claimed
EP-0703819-A1 METHOD OF MAKING COMPOSITE GAS SEPARATION MEMBRANES UOP (US) 1996-04-03 EP claimed
WO-1994029002-A1 COMPOSITE GAS SEPARATION MEMBRANES AND MAKING THEREOF UOP (US) 1994-12-22 WO claimed
WO-1992012120-A1 BIS(AMINOPHENOXY)NAPHTHALENES AND BIS(NITROPHENOXY)NAPHTHALENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-23 WO claimed
JP-5078482-A None JP disclosed
JP-7089932-A None JP disclosed
JP-11152333-A None JP disclosed
US-12313227-B2 LED filament and LED light bulb ZHEJIANG SUPER LIGHTING ELECTRIC APPLIANCE CO., LTD. (CN) 2025-05-27 US disclosed
US-20240288131-A1 LED FILAMENT AND LED LIGHT BULB ZHEJIANG SUPER LIGHTING ELECTRIC APPLIANCE CO., LTD. (CN) 2024-08-29 US disclosed
US-12060455-B2 LED filament and LED light bulb JIAXING SUPER LIGHTING ELECTRIC APPLIANCE CO., LTD (CN) 2024-08-13 US disclosed
WO-1992012120-A1 BIS(AMINOPHENOXY)NAPHTHALENES AND BIS(NITROPHENOXY)NAPHTHALENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-23 WO disclosed
WO-1992012120-A1 BIS(AMINOPHENOXY)NAPHTHALENES AND BIS(NITROPHENOXY)NAPHTHALENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-23 WO disclosed
EP-0489418-A1 Novel multicomponent fluid separation membranes L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1992-06-10 EP disclosed
EP-0488341-A2 Polyimide gas separation membranes and process of using same L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1992-06-03 EP disclosed
US-5085676-A Porous polymeric substrate and polyamide separating layer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-04 US disclosed
US-5076817-A Aromatic polyamides; selective E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288260-A1 MAIN-CHAIN BENZOXAZINE OLIGOMER COMPOSITIONS, AND METHOD FOR THE PREPARATION THEREOF AOX1, AOC1, AOC2 ALDH1A1 253/4885TDP1 453/4885CYP3A4 1166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.