Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12691945 | 1.00 | TSHR (0.53) | TSHRL3MBTL1POLBATMCACNA1B | |
| SCHEMBL5606439 | 0.85 | L3MBTL1 (0.54) | TSHRL3MBTL1POLBATMCACNA1B | |
| SCHEMBL11639599 | 0.80 | L3MBTL1 (0.56) | TSHRL3MBTL1POLBATMCACNA1B | |
| SCHEMBL11215406 | 0.79 | CACNA1B (0.63) | TSHRL3MBTL1CACNA1BADRA2CGAA | |
| SCHEMBL1341786 | 0.78 | TSHR (0.58) | TSHRL3MBTL1POLBATMCACNA1B | |
| SCHEMBL30994802 | 0.78 | CHRM2 (0.58) | L3MBTL1POLBGAAALDH1A1MAPT | |
| SCHEMBL1022424 | 0.78 | CHRM2 (0.58) | L3MBTL1POLBGAAALDH1A1MAPT | |
| SCHEMBL13067611 | 0.77 | HTR2A (0.56) | L3MBTL1CACNA1BLMNAMAPTSMN1; SMN2 | |
| SCHEMBL10870072 | 0.77 | TSHR (0.62) | TSHRL3MBTL1POLBATMADRA2C | |
| SCHEMBL7835963 | 0.77 | ADRA2C (0.58) | TSHRL3MBTL1POLBATMADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281180-B2 | Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same | NEW YORK UNIVERSITY (US) | 2025-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281180-B2 | Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same | WNT1, WNT3, WNT3A | TSHR 3550/4885L3MBTL1 2508/4885POLB 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.