Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542062 | 0.87 | HDAC6 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL31542078 | 0.86 | POLB (0.51) | DRD2TBXA2RIDH1TSHRALDH1A1 | |
| SCHEMBL31542051 | 0.72 | HDAC6 (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL31542054 | 0.72 | HDAC6 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL31542082 | 0.72 | POLB (0.63) | DRD2TBXA2RTSHRALDH1A1NPSR1 | |
| SCHEMBL31542079 | 0.71 | PLA2G2A (0.49) | DRD2TBXA2RPLA2G2AHDAC1HDAC2 | |
| SCHEMBL31542083 | 0.69 | POLB (0.56) | DRD2TBXA2RHDAC8HDAC6TSHR | |
| SCHEMBL31542077 | 0.68 | ALDH1A1 (0.57) | DRD2TBXA2RTSHRALDH1A1L3MBTL1 | |
| SCHEMBL7254637 | 0.68 | CNR1 (0.58) | DRD2TBXA2RALDH1A1MAPTNPSR1 | |
| SCHEMBL7411710 | 0.67 | NPC1 (0.60) | DRD2TBXA2RALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | disclosed |