Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542065 | 0.88 | HDAC6 (0.59) | HDAC1HDAC11HDAC8HDAC6HDAC2 | |
| SCHEMBL31542053 | 0.74 | HDAC6 (0.56) | HDAC1HDAC11HDAC8HDAC6HDAC2 | |
| SCHEMBL23240776 | 0.73 | PDE4A (0.53) | KDM4EALDH1A1TSHRAGTR1AGTR2 | |
| SCHEMBL31542070 | 0.72 | HDAC6 (0.62) | KDM4EALDH1A1HDAC1HDAC11HDAC8 | |
| SCHEMBL31542083 | 0.71 | POLB (0.56) | KDM4EALDH1A1TSHRDRD2TBXA2R | |
| SCHEMBL31542071 | 0.71 | DRD2 (0.50) | PLA2G2AALDH1A1TSHRHSD17B10DRD2 | |
| SCHEMBL23280181 | 0.70 | IDH1 (0.60) | KDM4EALDH1A1DRD2TBXA2RIDH1 | |
| SCHEMBL9198766 | 0.70 | AGTR1 (0.79) | DRD2TBXA2RAGTR1AGTR2TLR7 | |
| SCHEMBL9199291 | 0.68 | AGTR1 (0.79) | DRD2TBXA2RAGTR1AGTR2TLR7 | |
| SCHEMBL2883864 | 0.68 | DRD2 (0.71) | KDM4EDRD2TBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | disclosed |