Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316051 | 0.99 | KMT2A (0.67) | KMT2AMEN1MAPTUSP2TSHR | |
| SCHEMBL315428 | 0.92 | GHSR (0.56) | KMT2AMEN1MAPTTSHRALDH1A1 | |
| SCHEMBL316302 | 0.92 | GHSR (0.56) | KMT2AMEN1MAPTTSHRALDH1A1 | |
| SCHEMBL316059 | 0.90 | KMT2A (0.59) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL316641 | 0.80 | KMT2A (0.65) | KMT2AMEN1MAPTTSHRALDH1A1 | |
| SCHEMBL315598 | 0.78 | KMT2A (0.62) | KMT2AMEN1MAPTUSP2TSHR | |
| SCHEMBL315884 | 0.78 | KMT2A (0.70) | KMT2AMEN1MAPTUSP2TSHR | |
| SCHEMBL316325 | 0.78 | KMT2A (0.61) | KMT2AMEN1MAPTTSHRALDH1A1 | |
| SCHEMBL316159 | 0.77 | KMT2A (0.58) | KMT2AMEN1MAPTTSHRALDH1A1 | |
| SCHEMBL314979 | 0.77 | GHSR (0.62) | KMT2AMEN1MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093272-B2 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2012-01-10 | — | — | US | claimed |
| US-8093272-B2 | Heteroaryl substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2012-01-10 | — | — | US | disclosed |