Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 12/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546624 | 0.90 | LMNA (0.54) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL31546645 | 0.89 | SMN1; SMN2 (0.43) | MAPK1SMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL19616169 | 0.75 | HTT (0.52) | MAPK1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL16679575 | 0.74 | MAPK1 (0.49) | MAPK1MAPK3ROCK2ROCK1 | |
| SCHEMBL16679576 | 0.74 | MAPK1 (0.49) | MAPK1MAPK3ROCK2ROCK1 | |
| SCHEMBL31546661 | 0.74 | KMT2A (0.51) | MAPK1SMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL28257953 | 0.73 | MAPK1 (0.46) | MAPK1MEN1KMT2AMAPK3 | |
| SCHEMBL31546660 | 0.72 | LMNA (0.63) | LMNAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL31546602 | 0.72 | L3MBTL1 (0.54) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL28076472 | 0.72 | MAPK1 (0.47) | MAPK1LMNAMAPK3ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | disclosed |