Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546660 | 0.89 | LMNA (0.63) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL15664050 | 0.77 | ALDH1A1 (0.51) | KMT2ALMNAMEN1ALDH1A1MTOR | |
| SCHEMBL2568462 | 0.77 | MAPT (0.58) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL27656657 | 0.76 | LMNA (0.64) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL27656560 | 0.76 | LMNA (0.64) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL28034240 | 0.75 | PGR (0.51) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL31546658 | 0.74 | MAPK1 (0.45) | KMT2AMAPTLMNAMEN1NPC1 | |
| SCHEMBL17192840 | 0.74 | MAPT (0.53) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL28257375 | 0.74 | LMNA (0.61) | KMT2AMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL28411034 | 0.73 | LMNA (0.61) | KMT2AMAPTLMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | disclosed |