Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21195964 | 0.86 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2HPGDKDM4E | |
| SCHEMBL7015986 | 0.82 | MAPT (0.45) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL27344305 | 0.81 | ALDH1A1 (0.44) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL29105406 | 0.78 | NUDT1 (0.46) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL10181187 | 0.77 | ALDH1A1 (0.51) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL22902580 | 0.77 | IKBKB (0.53) | ALDH1A1SMN1; SMN2HSP90AA1HPGDKDM4E | |
| SCHEMBL28813636 | 0.76 | ALDH1A1 (0.54) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL8322183 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL30846439 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL574989 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBLMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101598-A1 | BI-CYCLIC PYRIMIDINE COMPOUNDS, METHODS AND USES THEREOF | ZENO MANAGEMENT, INC. (US) | 2025-05-15 | — | — | WO | disclosed |