Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028862 | 0.88 | METAP2 (0.45) | LMNAMDH2MMP1MMP2MMP9 | |
| SCHEMBL31568226 | 0.83 | RAB9A (0.49) | ALDH1A1MAPTALOX15 | |
| SCHEMBL31568241 | 0.77 | LMNA (0.45) | LMNAMDH2MMP1MMP9MMP13 | |
| SCHEMBL30714199 | 0.77 | L3MBTL1 (0.41) | MDH2MMP1MMP2MMP9MMP13 | |
| SCHEMBL31503371 | 0.77 | MMP1 (0.38) | LMNAMMP1MMP2MMP9MMP13 | |
| SCHEMBL26088987 | 0.76 | HDAC1 (0.65) | HDAC1HDAC6MDH2HDAC8ALDH1A1 | |
| SCHEMBL12329247 | 0.74 | LMNA (0.43) | LMNAMDH2MMP1MMP9MMP13 | |
| SCHEMBL1556025 | 0.74 | HDAC1 (0.60) | HDAC1HDAC6HDAC8 | |
| SCHEMBL31568211 | 0.73 | MAPT (0.44) | LMNAMDH2PIK3R1PIK3CAKDM4E | |
| SCHEMBL31568208 | 0.73 | MAPT (0.42) | LMNAMDH2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587438-A1 | BICYCLIC COMPOUNDS AS CDK INHIBITORS | BeiGene Switzerland GmbH (CH) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894890-A | Bicyclic compounds as CDK inhibitors | 百济神州(苏州)生物科技有限公司 | 2025-04-25 | — | — | CN | disclosed |