Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913506 | 0.83 | MAPT (1.00) | MAPTRECQLLMNASIRT6ALDH1A1 | |
| SCHEMBL12312113 | 0.82 | ALDH1A1 (0.64) | MAPTRECQLLMNASIRT6ALDH1A1 | |
| Fluoride SCHEMBL11555512 | 0.82 | MAPT (0.97) | MAPTRECQLLMNASIRT6ALDH1A1 | |
| SCHEMBL31570658 | 0.81 | MAPT (0.43) | MAPTRECQLLMNAALDH1A1MAPK1 | |
| SCHEMBL855195 | 0.79 | SIRT6 (0.64) | MAPTLMNASIRT6ALDH1A1POLB | |
| SCHEMBL3109069 | 0.78 | LMNA (1.00) | MAPTRECQLLMNASIRT6ALDH1A1 | |
| SCHEMBL30059159 | 0.78 | LMNA (1.00) | MAPTRECQLLMNASIRT6ALDH1A1 | |
| SCHEMBL25877527 | 0.78 | LMNA (0.94) | MAPTRECQLLMNASIRT6ALDH1A1 | |
| SCHEMBL24196347 | 0.77 | MAPT (0.40) | MAPTRECQLLMNACYP1A2CYP2C19 | |
| SCHEMBL8074050 | 0.77 | LMNA (0.97) | MAPTRECQLLMNASIRT6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099451-A1 | NEW COMPOUNDS AND METHODS | Transition Bio Limited (GB) | 2025-05-15 | — | — | WO | disclosed |