Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26971010 | 1.00 | PDXK (0.41) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7992256 | 0.81 | CYP11B2 (0.32) | MAPK1CYP11B2 | |
| SCHEMBL18614801 | 0.80 | MAPK1 (0.34) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL21737250 | 0.79 | NOS3 (0.38) | ALDH1A1MAPK1CYP11B2MKNK1MKNK2 | |
| SCHEMBL29411201 | 0.78 | PDXK (0.44) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL992612 | 0.78 | PDXK (0.44) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14932548 | 0.76 | ALDH1A1 (0.41) | PDXKALDH1A1GAAHTT | |
| SCHEMBL393029 | 0.75 | PDXK (0.33) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL21722863 | 0.75 | LMNA (0.34) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18795074 | 0.75 | ALDH1A1 (0.41) | PDXKALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096751-A1 | MACROCYCLIC INHIBITORS OF ATP CITRATE LYASE | ESPERION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |