Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31575020 | 0.78 | NQO2 (0.34) | L3MBTL1 | |
| SCHEMBL30706223 | 0.76 | LMNA (0.37) | LMNATP53THRBTLR9L3MBTL1 | |
| SCHEMBL31330822 | 0.74 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL30910209 | 0.71 | — | — | |
| SCHEMBL20389071 | 0.70 | ALKBH5 (0.43) | LMNA | |
| SCHEMBL31444008 | 0.70 | PKM (0.43) | LMNATHRBL3MBTL1 | |
| SCHEMBL25079216 | 0.66 | MAPT (0.41) | LMNATP53THRB | |
| SCHEMBL30112337 | 0.66 | PDGFRA (0.41) | L3MBTL1 | |
| SCHEMBL17674125 | 0.66 | PDGFRA (0.41) | L3MBTL1 | |
| SCHEMBL31520847 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101571-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-X L DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |