Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309735 | 0.76 | ALDH1A1 (0.69) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL8727685 | 0.72 | ALDH1A1 (0.45) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL245919 | 0.70 | CXCR4 (0.81) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL31577784 | 0.70 | TAAR1 (0.46) | SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL152631 | 0.70 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| Benzene SCHEMBL27761330 | 0.70 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL6138636 | 0.70 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL83548 | 0.70 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL276363 | 0.70 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL5573232 | 0.70 | CXCR4 (0.78) | SIGMAR1CXCR4MEN1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163042-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163042-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | SIGMAR1 3199/4885CXCR4 2507/4885MEN1 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.