Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30931929 | 0.87 | RAB9A (0.47) | L3MBTL1MAPTRAB9ANPC1ATM | |
| SCHEMBL31587164 | 0.84 | MAPT (0.44) | L3MBTL1MAPTRAB9ANPC1ATM | |
| SCHEMBL31587216 | 0.83 | L3MBTL1 (0.38) | L3MBTL1MAPTRAB9ANPC1ATM | |
| SCHEMBL31587124 | 0.77 | KDM5A (0.50) | MAPTKDM4EALDH1A1RECQLKDM5A | |
| SCHEMBL31587440 | 0.76 | IRAK4 (0.36) | L3MBTL1MAPTRAB9ANPC1ATM | |
| SCHEMBL31587090 | 0.76 | GABRA5 (0.39) | L3MBTL1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15886672 | 0.74 | RAB9A (0.85) | L3MBTL1MAPTRAB9ANPC1ATM | |
| SCHEMBL869497 | 0.74 | KMT2A (0.53) | L3MBTL1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29684288 | 0.74 | KMT2A (0.53) | L3MBTL1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1321573 | 0.74 | MEN1 (0.59) | L3MBTL1MAPTNPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | disclosed |