Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TPO | P07202 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.38 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587424 | 0.81 | LMNA (0.45) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL15603510 | 0.79 | HDAC3 (0.55) | KDM4ECYP2C9HSD17B10HCAR2ALDH1A1 | |
| SCHEMBL31587288 | 0.78 | KDM5A (0.50) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL31587585 | 0.78 | KDM5A (0.52) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL9965961 | 0.78 | MPO (0.46) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL31587216 | 0.77 | L3MBTL1 (0.38) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL31587362 | 0.77 | L3MBTL1 (0.49) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL15519476 | 0.77 | AR (0.41) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL3193063 | 0.76 | ALKBH2 (0.53) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL31524136 | 0.76 | ALKBH2 (0.53) | KDM5AKDM4CKDM5BKDM2BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | disclosed |