Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 6/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 6/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 6/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 6/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 6/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 6/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25395509 | 1.00 | PNLIP (0.45) | PNLIPPTPN2PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL25396431 | 1.00 | PNLIP (0.45) | PNLIPPTPN2PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL30585216 | 1.00 | PNLIP (0.45) | PNLIPPTPN2PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL25395046 | 0.85 | PNLIP (0.58) | PNLIPPTPN2PTPN1CYP3A4CYP19A1 | |
| SCHEMBL25397921 | 0.85 | PNLIP (0.58) | PNLIPPTPN2PTPN1CYP3A4CYP19A1 | |
| SCHEMBL25435569 | 0.85 | PNLIP (0.58) | PNLIPPTPN2PTPN1CYP3A4CYP19A1 | |
| SCHEMBL30585231 | 0.85 | PNLIP (0.58) | PNLIPPTPN2PTPN1CYP3A4CYP19A1 | |
| SCHEMBL25433937 | 0.81 | ALDH1A1 (0.41) | PNLIPPTPN2PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL31592754 | 0.81 | ALDH1A1 (0.41) | PNLIPPTPN2PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL25437972 | 0.81 | ALDH1A1 (0.41) | PNLIPPTPN2PTPN1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171391-A1 | PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES | FIRMENICH SA (CH) | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171391-A1 | PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES | POR, NDUFV1, NDUFV2 | PNLIP 1966/4885PTPN2 4240/4885PTPN1 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.