Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954958 | 0.81 | NOS3 (0.36) | NOS3NOS2GLAPOLBGAA | |
| SCHEMBL27979595 | 0.81 | NOS3 (0.36) | NOS3NOS2GLAPOLBGAA | |
| SCHEMBL3155605 | 0.78 | — | — | |
| SCHEMBL157195 | 0.74 | NOS3 (0.46) | NOS3NOS2LOXL2LOXGLA | |
| SCHEMBL29435659 | 0.74 | NOS3 (0.46) | NOS3NOS2LOXL2LOXGLA | |
| SCHEMBL3154225 | 0.74 | NFE2L2 (0.42) | — | |
| SCHEMBL30356572 | 0.72 | NOS3 (0.41) | NOS3NOS2LOXL2LOXGLA | |
| SCHEMBL31097846 | 0.71 | NOS2 (0.39) | NOS3NOS2LOXL2GLAPOLB | |
| SCHEMBL20088854 | 0.71 | NOS2 (0.39) | NOS3NOS2LOXL2GLAPOLB | |
| SCHEMBL31358429 | 0.71 | NOS3 (0.39) | NOS3NOS2LOXL2LOXGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723156-B1 | PROCESS FOR THE PREPARATION OF PYRIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-01-21 | — | — | EP | disclosed |
| US-7687632-B2 | Process for the preparation of pyridine derivatives | DOW AGROSCIENCES LLC (US) | 2010-03-30 | — | — | US | disclosed |
| US-20070249837-A1 | Process for the Preparation of Pyridine Derivatives | CORTEVA AGRISCIENCE LLC | 2007-10-25 | — | — | US | disclosed |
| EP-1723156-A1 | PROCESS FOR THE PREPARATION OF PYRIDINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005063780-A1 | PROCESS FOR THE PREPARATION OF PYRIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249837-A1 | Process for the Preparation of Pyridine Derivatives | CBR1, CBR3, CCNT1 | NOS3 1032/4885NOS2 579/4885LOXL2 3483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.