Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | POLG | P54098 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26188659 | 0.76 | NPC1 (0.36) | NPC1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31599575 | 0.76 | MAPK14 (0.35) | NPC1ABCB11POLA1POLGFAP | |
| SCHEMBL20774171 | 0.74 | P2RX7 (0.49) | TDP1ABCB11POLA1POLGFAP | |
| SCHEMBL3730211 | 0.73 | HSP90AB1 (0.49) | HDAC6 | |
| SCHEMBL3848710 | 0.72 | LMNA (0.42) | NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL29530593 | 0.71 | BRD4 (0.38) | FGFR1FGFR4HSD17B10SMN1; SMN2TSHR | |
| SCHEMBL3727460 | 0.71 | HSP90AB1 (0.38) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL6589975 | 0.70 | SMN1; SMN2 (0.53) | NPC1KMT2ACYP2C9CYP2C19RAB9A | |
| SCHEMBL5565180 | 0.70 | TNF (0.43) | GAAPOLBNPSR1ALDH1A1HPGD | |
| SCHEMBL9601170 | 0.70 | TRPA1 (0.47) | NPC1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111251-A1 | COMPOUNDS THAT INHIBIT POLO-LIKE KINASE 4 | EXELIXIS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |