Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 5/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599636 | 1.00 | SPR (0.36) | SPRGPR119JAK3RETOPRM1 | |
| SCHEMBL2732032 | 0.80 | GPR119 (0.47) | GPR119 | |
| SCHEMBL14085918 | 0.76 | NPFFR1 (0.47) | — | |
| SCHEMBL18291699 | 0.74 | JAK3 (0.40) | SPRGPR119JAK3RET | |
| SCHEMBL31599783 | 0.70 | USP2 (0.35) | SPRJAK3OPRM1NR1H2GRIN2B | |
| SCHEMBL18390217 | 0.70 | JAK3 (0.38) | SPRJAK3RETNR1H2GRIN2B | |
| SCHEMBL30761069 | 0.69 | HSD11B1 (0.38) | SPRJAK3RETGRIN2BGRIN2C | |
| SCHEMBL31713527 | 0.68 | CYP3A4 (0.46) | GPR119JAK3RETNR1H2 | |
| SCHEMBL23179862 | 0.68 | KMT2A (0.38) | — | |
| SCHEMBL12547430 | 0.68 | CYP2D6 (0.53) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111251-A1 | COMPOUNDS THAT INHIBIT POLO-LIKE KINASE 4 | EXELIXIS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |