Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810316 | 0.94 | CTSS (0.35) | CNR2CA14CTSSCTSKALOX5 | |
| SCHEMBL6680983 | 0.92 | CTSK (0.37) | CA14CTSSCTSKALOX5HDAC1 | |
| SCHEMBL15166440 | 0.90 | SLC6A1 (0.36) | CNR2CA14 | |
| SCHEMBL27035609 | 0.84 | CA14 (0.38) | CNR2CA14NR1H2CTSSCTSK | |
| SCHEMBL24890720 | 0.83 | CNR2 (0.36) | CNR2CA14NR1H2KMT2AALOX5 | |
| SCHEMBL4789369 | 0.82 | ALDH1A1 (0.35) | CA14CTSSNFKB1NFKB2RELA | |
| SCHEMBL78691 | 0.82 | CA14 (0.41) | CA14CTSSKMT2ANFKB1NFKB2 | |
| SCHEMBL21867153 | 0.81 | CA14 (0.40) | CNR2CA14NR1H2CTSSCTSK | |
| SCHEMBL191623 | 0.80 | CNR2 (0.35) | CNR2CA14NR1H2CTSSCTSK | |
| SCHEMBL8165566 | 0.80 | ALOX5 (0.41) | CNR2CA14CTSSCTSKALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109540-A1 | MACROCYCLIC COMPOUNDS AS KIF18A INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-05-30 | — | — | WO | disclosed |