Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | STAT5B | P51692 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31609599 | 0.86 | AKT1 (0.39) | AKT1STAT5BHDAC3HDAC1HDAC2 | |
| SCHEMBL4194363 | 0.85 | CHRM2 (0.43) | GRM2POLBF2CHRM2CHRM1 | |
| SCHEMBL31609600 | 0.81 | F2 (0.32) | AKT1STAT5BHDAC3HDAC1HDAC2 | |
| SCHEMBL31609582 | 0.76 | HDAC1 (0.41) | AKT1STAT5BHDAC3HDAC1HDAC2 | |
| SCHEMBL7473118 | 0.76 | LTB4R2 (0.49) | AKT1STAT5BHDAC3HDAC1HDAC2 | |
| SCHEMBL22042475 | 0.75 | TRPM8 (0.45) | AKT1STAT5BHDAC3HDAC1HDAC2 | |
| SCHEMBL23912387 | 0.75 | NR1H4 (0.46) | AKT1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL4315970 | 0.75 | PTGES (0.54) | AKT1STAT5BHDAC3HDAC1HDAC2 | |
| SCHEMBL19922245 | 0.75 | AKT1 (0.47) | AKT1STAT5BHDAC3HDAC1HDAC2 | |
| SCHEMBL5906827 | 0.75 | CHRM2 (0.50) | AKT1HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12486232-B2 | Method for preparing meta-functionalized pyridine compound | NANKAI UNIVERSITY (CN) | 2025-12-02 | — | — | US | disclosed |
| US-20250179021-A1 | Method For Preparing Meta-Functionalized Pyridine Compound | CNBM RESEARCH INSTITUTE FOR ADVANCED GLASS MATERIALS GROUP CO., LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486232-B2 | Method for preparing meta-functionalized pyridine compound | GAPVD1, SKP1, PDXK | AKT1 4073/4885STAT5B 3999/4885HDAC3 4471/4885 |
| US-20250179021-A1 | Method For Preparing Meta-Functionalized Pyridine Compound | GAPVD1, SKP1, PDXK | AKT1 4073/4885STAT5B 3999/4885HDAC3 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.